I write to organise ideas before they become projects. Some pieces stay in my notebook; the ones that survive land here as essays and occasionally as adapted versions on my LinkedIn page. I broadly group my writing, for the time being, into three major cluster: Diagnostics Sovereignty, Precision Diagnostics, and a more broad category of Systems and Futures.
Published on Linkedin on Nov 23rd I visited Wuhan once, in 2004, teaching for a couple of weeks as part of EMBO’s World Program. I can’t claim the trip left me with profound insights about China – the city was unremarkable if enormous, nothing that prepared me for what it would become or mean to…
Published on LinkedIn on Nov 20th In Part 1/2 (https://www.linkedin.com/pulse/rebuilding-case-diagnostics-investment-12-reflections-pereira-leal-swvbf), I discussed why diagnostics face a systematic funding gap despite being essential infrastructure for precision medicine, and outlined five strategic directions for entrepreneurs building diagnostic companies. Those reflections emerged from building Ophiomics and follow from the reflection I’ve been making for my book, Precision Diagnostics:…
Published on LinkedIn on Nov 17th The diagnostics sector faces a paradox: we’re living through a precision medicine revolution, yet the tools that make precision medicine possible remain chronically underfunded. In 2023-2024, diagnostics captured just $2.2 billion in global venture funding, while AI companies raised over $100 billion globally in 2024. Even within healthcare, nearly…
Published on linkedin A few days after Web Summit Lisbon 2025, one impression remains very clear to me: how differently national hashtag#innovationecosystems choose to present themselves. As someone working at the intersection of precision diagnostics and ecosystem development, I pay attention not only to the technologies on display but to the systems behind them. One of the…
Published on Linkedin on November 8th, 2025 Reading Qatar’s latest precision medicine and national strategy reports as my flight approached Doha, I found myself genuinely impressed and, as a veteran of biomedical strategy, more than a little astonished. In barely a generation, Qatar has accomplished what it has taken the world’s leading medical innovation centers…
Published on Linkedin on October 12, 2025 I just spent three intense days at BioSpain 2025 (https://www.asebio.com/en/news-events/news/biospain-2025-closes-record-attendance-and-passes-baton-bilbao-2026-host-city), participating in a most intense (!) partnering marathon, and also had the privilege of participating in two roundtables. One, wearing the hat of VP of P-BIO (https://p-bio.org), was entitled “𝘍𝘳𝘰𝘮 𝘙𝘦𝘨𝘪𝘰𝘯 𝘵𝘰 𝘎𝘭𝘰𝘣𝘢𝘭: 𝘉𝘶𝘪𝘭𝘥𝘪𝘯𝘨 𝘚𝘤𝘢𝘭𝘢𝘣𝘭𝘦 𝘉𝘪𝘰𝘵𝘦𝘤𝘩 𝘵𝘩𝘳𝘰𝘶𝘨𝘩 𝘚𝘤𝘪𝘦𝘯𝘵𝘪𝘧𝘪𝘤…
At 35, Sarah suffered a heart attack that a €30 genetic test could have prevented. Her story isn’t unusual, it’s a mirror of how health systems worldwide confuse “standard care” with equity. Sarah, a 34-year-old teacher, had visited her GP complaining of fatigue and chest tightness during exercise. Her cholesterol was significantly elevated at 8.2…
The European Union proclaimed its 1+ Million Genomes initiative in April 2018, with 26 Member States committing to create federated genomic infrastructure. Six years later, we can’t even determine how many genomes Europe has actually sequenced. 🇪🇺 EU 27 Countries: ??? genomes completed – No consolidated reporting after 6 years Try finding the actual genome…
“70% of clinical decisions depend on diagnostics.” You’ve seen this statistic, but it hides an important detail: timing. The acuity gradient: Lab testing occurs in 98% of inpatient encounters, 56% in emergency departments, but only 29% in outpatient settings (Ngo et al., 2017): diagnostics concentrate where disease is most advanced. Prevention is neglected: Evidence-based guidelines…
Published on Linkedin on August 3rd, 2025 While everyone chases longevity drugs, the real fountain of youth sits in your liver In the ever-expanding dialogue around longevity in a medical setting, we hear a lot about telomeres, senescence, mitochondrial decline, DNA repair, VO2 Max, stem cells and, unfortunately, an endless stream of pseudo-science powering rising…